Form and Refine the Research Question

A well-crafted research question is the foundation of a successful research study. A research question guides the entire research process, from design to analysis. The research design dictates how you’ll gather and analyze data to answer that question, shaping the study’s structure and methods. 

An image of the "research cycle". The box at the bottom right says "Form and refine the research question" and is highlighted while the other boxes are greyed out.

The Research Question

A strong question not only guides the direction of your investigation but also ensures that your study is focused, relevant, and feasible. Different frameworks exist to help researchers craft focused, feasible, and methodologically aligned questions.

General Research Question Development

FINER stands for Feasibility Interesting Novel Ethical Relevant. This framework is used to evaluate the strength and practicality of a research question.

Frameworks for Quantitative Research

PICO stands for Patient/Problem Intervention Comparison Outcome. It can help structure questions for intervention-based studies.

PICOT adds Timeframe to the above framework. It is useful in clinical trials, prognosis or follow-up studies.

Frameworks for Qualitative Research

PICo stands for Population Interest (phenomenon) Context. It works best for qualitative research with a clearly defined population or context.

SPIDER stands for Sample Phenomenon of Interest Design Evaluation Research type. This framework is helpful for qualitative evidence synthesis or mixed-methods review.

For more information, review the following resources:


*DFM faculty members can access full text articles from the McMaster Health Sciences Library using your MacID. To request your MacID, or if you’re having issues, please email Faculty Relations at fmappts@mcmaster.ca.

Connect with Us

For support, feedback, or to suggest a resource, email pcrc@mcmaster.ca